Trade names Trofodermin-S Legal status CA: Schedule IV PubChem CID 68947 Molar mass 322.869 g/mol | ATC code none CAS Number 1093-58-9 DrugBank DB01521 | |
 | ||
Clostebol (INN), also known as 4-chlorotestosterone, usually as the ester clostebol acetate, is a synthetic anabolic androgenic steroid (AAS). Clostebol is the 4-chloro derivative of the natural hormone testosterone. The chlorination prevents conversion to dihydrotestosterone (DHT) while also rendering the chemical incapable of conversion to estrogen. Although usually used as an ester including clostebol acetate (Macrobin, Steranabol, Alfa-Trofodermin, Megagrisevit), clostebol caproate (Macrobin-Depot), or clostebol propionate (Yonchlon), unmodified/non-esterified clostebol is also marketed, under the brand name Trofodermin-S in Mexico.
Contents
- How to pronounce clostebol
- Non doping uses
- Nutritional supplements
- Publicized abuse cases
- Regulation
- References
Clostebol is a weak AAS with potential use as a performance enhancing drug. It is currently banned by the World Anti-Doping Agency. Oral Turinabol, combining the chemical structures of clostebol and dianabol, was widely used in the East German state-sponsored doping program.
How to pronounce clostebol
Non-doping uses
Clostebol acetate ointment has ophthalmological and dermatological use.
Nutritional supplements
A related anabolic steroid, methylclostebol, is a common additive in so-called dietary supplements, generally listed in the convoluted form 4-chloro-17α-methyl-androst-4-en-17β-ol-3-one.
Publicized abuse cases
Use of clostebol has led to the suspension of a number of athletes in various sports including Freddy Galvis of the Philadelphia Phillies in 2012, Dee Gordon of the Miami Marlins in 2016, and Olympic athlete Viktoria Orsi Toth in 2016.
In 2016, urinalysis resulted in Therese Johaug testing positive for clostebol.
Regulation
In the US, clostebol is listed as a Schedule III substance.