Residence Cambridge Name Chris Dobson | Fields Chemistry, Biophysics | |
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Born Christopher Martin Dobson
October 8, 1949 (age 74) ( 1949-10-08 ) Institutions St John's College, Cambridge
University of Cambridge
Harvard University Alma mater University of Oxford (BA, DPhil) Thesis The conformation of lysozyme in solution (1975) Notable awards FRS
FMedSci
FAAS
Davy Medal (2005)
Royal Medal (2009)
Heineken Prize (2014) Books Foundations of Chemical Biology Education Harvard University, University of Oxford | ||
Chemistry protein molecules chris dobson
Christopher Martin Dobson, FRS, FMedSci (born 8 October 1949) is a British chemist, who is the John Humphrey Plummer Professor of Chemical and Structural Biology in the Department of Chemistry at the University of Cambridge, and Master of St John's College, Cambridge.
Contents
- Chemistry protein molecules chris dobson
- Profiting from experiences chris dobson
- Education
- Research
- Career
- Awards and honours
- References
Profiting from experiences chris dobson
Education
Dobson completed a Bachelor of Arts and D.Phil at the University of Oxford (Keble and Merton Colleges).
Research
Dobson's research is largely concerned with protein folding and misfolding, and its links with medical disorders particularly Alzheimer's and Parkinson's diseases. His research interests are focused on protein molecules, and particularly on defining the fundamental principles by which they fold to generate function and biological activity, and yet can misfold to generate toxicity and disease. His studies are highly interdisciplinary and collaborative, and make use of a very wide range of techniques, encompassing theory as well as experiment. The Dobson group based at the Department of Chemistry, University of Cambridge is particularly interested in the discovery of the nature, properties, mechanism of formation and biological significance of the ‘misfolded’ amyloid state of proteins. Amyloid-related diseases include whole-body disorders such as the systemic amyloidoses, neuronal disorders such as Alzheimer’s and Parkinson’s diseases, and other organ-specific disorders such as type II diabetes. The major goals are the elucidation of the general molecular principles that underlie this whole family of medical conditions, which are now becoming a major threat to human health and social harmony across the modern world, and the generation of a firm foundation for the rational and effective prevention and treatment of these debilitating and usually fatal conditions. Dobson is an author or co-author of nearly 700 papers and review articles, including more than 30 in Nature and Science, which have been cited over 50,000 times. His current h-index is 110.
Career
Dobson held Research Fellowships at Merton College and then Linacre College before working at Harvard University. He returned to Oxford in 1980 as a Fellow of Lady Margaret Hall, Oxford and as a University Lecturer in Chemistry, later receiving promotions to Reader, then Professor, of Chemistry. Dobson has been at Cambridge since 2001 and has been Master of St John's College, Cambridge since 2007.
Awards and honours
In 2009 Dobson was awarded the Royal Medal by the Royal Society "for his outstanding contributions to the understanding of the mechanisms of protein folding and mis-folding, and the implications for disease", and in 2014 he received both the Heineken Prize for Biochemistry and Biophysics and the Feltrinelli International Prize for Medicine. Dobson was elected a Fellow of the Royal Society (FRS) in 1996. His nomination reads:
Dobson's other accolades include: