Centennial Airlines was founded in Laramie, Wyoming and began operations on June 15, 1981 with an initial route linking Denver to Laramie and Worland, Wyoming using a single Cessna 414 aircraft. The carrier flew until June 15, 1987 when it was merged into Mesa Airlines. Centennial was first based in Laramie, Wyoming, moved its offices to Worland, then to Cheyenne for a brief time in 1982, then back to Worland.
Centennial served Denver, Colorado, Billings, Montana; Logan and Salt Lake City, Utah; Casper, Cheyenne, Cody, Jackson, Lander, Laramie, Rawlins, Riverton, Rock Springs and Worland, Wyoming.
Routes operated include:
Salt Lake City-Logan-Riverton-Worland-Cody
The fleet included two Beechcraft 1900's and one Beechcraft 99 at the time of its merger with Mesa Airlines.