Entrez 11052 | Ensembl ENSG00000111605 | |
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Aliases CPSF6, CFIM, CFIM68, HPBRII-4, HPBRII-7, cleavage and polyadenylation specific factor 6 External IDs MGI: 1913948 HomoloGene: 134126 GeneCards: CPSF6 | ||
Cleavage and polyadenylation specificity factor subunit 6 is a protein that in humans is encoded by the CPSF6 gene.
Contents
Function
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitement of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.
Interactions
CPSF6 has been shown to interact with WWP1 and PLSCR1.
References
CPSF6 Wikipedia(Text) CC BY-SA