Harman Patil (Editor)

COUP TFI

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Species
  
Human

Entrez
  
7025

Human
  
Mouse

Ensembl
  
ENSG00000175745

COUP-TFI

Aliases
  
NR2F1, BBOAS, BBSOAS, COUP-TFI, EAR-3, EAR3, ERBAL3, NR2F2, SVP44, TCFCOUP1, TFCOUP1, nuclear receptor subfamily 2 group F member 1

External IDs
  
MGI: 1352451 HomoloGene: 21158 GeneCards: NR2F1

COUP-TF1 (COUP Transcription Factor 1) also known as NR2F1 (Nuclear Receptor subfamily 2, group F, member 1) is a protein that in humans is encoded by the NR2F1 gene. This protein is a member of nuclear hormone receptor family of steroid hormone receptors.

Contents

Function

Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription. COUP-TF1 binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif.

Interactions

COUP-TFI has been shown to interact with:

  • BCL11A,
  • BCL11B,
  • COPS2, and
  • ESR1.

    • References

    COUP-TFI Wikipedia
    (Text) CC BY-SA


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