Siddhesh Joshi (Editor)

Alexander Rich

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Nationality  USA
Influenced by  Francis Crick
Fields  Biophysics

Name  Alexander Rich
Influences  Francis Crick
Alexander Rich co0bgcomrfimage585wBoston20112020201505

Born  November 15, 1924 Hartford, Connecticut, USA (1924-11-15)
Residence  Cambridge, Massachusetts, USA
Institutions  Massachusetts Institute of Technology
Alma mater  Harvard University, USA
Known for  discoverer of polysomes and Z-DNA
Died  April 27, 2015, Boston, Massachusetts, United States
Education  Harvard Medical School (1949), Harvard University (1947)
Awards  Guggenheim Fellowship for Natural Sciences, US & Canada

Organizations founded  Repligen, Alkermes

Alexander rich mit the discovery of polynucleotide hybridization

Alexander Rich (November 15, 1924 – April 27, 2015) was an American biologist and biophysicist. He was the William Thompson Sedgwick Professor of Biophysics at MIT (since 1958) and Harvard Medical School. Dr. Rich earned both an A.B. (magna cum laude) and an M.D. (cum laude) from Harvard University. He was a post-doc of Linus Pauling along with James Watson. During this time he was a member of the RNA Tie Club, a social and discussion group which attacked the question of how DNA encodes proteins. He had over 600 publications to his name.


Rich was married to Jane King and is survived by four children: Benjamin, Josiah, Rebecca, and Jessica Rich Sturley.

Alexander Rich Alexander Rich dies at 90 MIT News

Born in Hartford, Connecticut, Rich was the founder of Alkermes and was a director beginning in 1987. Dr. Rich was Co-Chairman of the Board of Directors of Repligen Corporation, a biopharmaceutical company. He was also a member of the Board of Directors for Profectus BioSciences, Inc. He also served on the editorial board of Genomics and the Journal of Biomolecular Structure and Dynamics.

Alexander Rich In Memoriam Alexander Rich

In 1963, Rich discovered polysomes: clusters of ribosomes which read one strand of mRNA simultaneously.

Alexander Rich Oral History Alex Rich

In 1979, Rich and co-workers at MIT grew a crystal of Z-DNA. This was the first crystal structure of any form of DNA. After 26 years of attempts, Rich et al. finally crystallised the junction box of B- and Z-DNA. Their results were published in an October 2005 Nature journal. Whenever Z-DNA forms, there must be two junction boxes that allow the flip back to the canonical B-form of DNA. Rich died on April 27, 2015, aged 90.

Alexander Rich John Simon Guggenheim Foundation Alexander Rich

2008 welch award in chemistry alexander rich

List of awards and prizes received

Alexander Rich Alexander Rich MIT The Discovery of Polynucleotide Hybridization

  • a member of the National Academy of Sciences (appointed 17 April 1978)
  • a member of the American Academy of Arts and Sciences
  • a member of the Philosophical Society
  • a member of the French Academy of Sciences
  • a member of the Institute of Medicine
  • a member of the Scientific Advisory Board of U.S. Genomics, Inc.
  • President Bill Clinton recognized his outstanding scientific achievements with the National Medal of Science in 1995.
  • The Bower Award and Prize for Achievement in Science (2000)
  • 2001 William Procter Prize for Scientific Achievement
  • 2008 Welch Award in Chemistry: "For outstanding contributions to the understanding of the chemical and biochemical mechanisms in maintaining a living cell".
  • Awards and prizes

  • Sigma Xi Proctor Prize, Raleigh, NC (2001)
  • Bower Award and Prize, the Franklin Institute, Philadelphia, PA (2000)
  • National Medal of Science, Washington, DC (1995)
  • Linus Pauling Medal, American Chemical Society, Northwest Sections (1995)
  • Lewis S. Rosenstiel Award in Basic Biomedical Research, Brandeis Univ., Waltham, MA (1983)
  • James R. Killian Faculty Achievement Award, Massachusetts Institute of Technology (1980)
  • Presidential Award, New York Academy of Science, New York, NY (1977)
  • Theodore van Karmen Award for Viking Mars Mission, Washington, DC (1976)
  • Skylab Achievement Award, National Aeronautics and Space Administration, Washington, DC (1974)
  • Academies

  • Foreign Member, Russian Academy of Sciences, Moscow, Russia (1994)
  • Honorary Member, Japanese Biochemical Society, Tokyo, Japan (1986)
  • Foreign Member, French Academy of Sciences, Paris, France (1984)
  • Honorary Doctorate, Federal University of Rio de Janeiro, Brazil (1981)
  • American Philosophical Society, Philadelphia, PA (1980)
  • Pontifical Academy of Sciences (1978)
  • National Academy of Sciences, Washington, DC (1970)
  • Fellow, American Association for the Advancement of Science, Washington, DC (1965)
  • Fellow, Guggenheim Foundation (1963)
  • Fellow, American Academy of Arts and Sciences, Boston, MA (1959)
  • Fellow, National Research Council, Washington, DC (1949–51).
  • References

    Alexander Rich Wikipedia