Formula C3H7O7P | Molar mass 186.06 g/mol | |
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3-Phosphoglyceric acid (3PG), or glycerate 3-phosphate (GP), is a biochemically significant 3-carbon molecule that is a metabolic intermediate in both glycolysis and the Calvin cycle. This chemical is often termed PGA when referring to the Calvin cycle. In the Calvin cycle, 3-Phosphoglycerate is the product of the spontaneous split of an unstable 6-carbon intermediate formed by CO2 fixation. Thus, two 3-phosphoglycerate molecules are produced for each molecule of CO2 fixed.
Contents
Glycolysis
Compound C00236 at KEGG Pathway Database. Enzyme 2.7.2.3 at KEGG Pathway Database. Compound C00197 at KEGG Pathway Database. Enzyme 5.4.2.1 at KEGG Pathway Database. Compound C00631 at KEGG Pathway Database.
Click on genes, proteins and metabolites below to link to respective articles.
Calvin cycle
In the light-independent reactions (also known as the Calvin cycle), two 3-phosphoglycerate molecules are synthesized, one of which continues through the Calvin cycle to be regenerated to RuBP and the other is reduced to form one molecule of glyceraldehyde 3-phosphate (G3P). This is the first compound formed during the C3 or Calvin cycle. It is a reactive biomolecule that is easily reduced.
Amino acid synthesis
Glycerate 3-phosphate is also a precursor for serine, which, in turn, can create cysteine and glycine through the homocysteine cycle.