29 January - Bolton Abbey, a Yorkshire priory, is closed down as part of the Dissolution of the Monasteries.
16 February - Thetford Priory is closed down as part of the Dissolution of the Monasteries.
23 March - Waltham Abbey is the last abbey to close as part of the Dissolution of the Monasteries.
April - The cathedral priories of Canterbury and Rochester are transformed into secular cathedral chapters, concluding the Dissolution of the Monasteries.
Publication of The Byrth of Mankynde, the first printed book in English on obstetrics, and one of the first published in England to include engraved plates.
March - Third Succession Act, reinstating Princesses Mary and Elizabeth to the line of succession to the English throne, given Royal Assent (having been passed by Parliament in July 1543).
April - Posthumous publication of Cardinal John Fisher's Psalmi seu precationes in the original and in an anonymous English translation by its sponsor, Queen Catherine Parr.
29 May - Publication of Catherine Parr's Prayers or Meditations, the first book published by an English queen under her own name, and the King's Primer, another devotional work overseen by her.
Edward Seymour begins the construction of Somerset House, London.
Treason Act makes it high treason to interrupt the line of succession to the throne established by the Act of Succession; and requires two witnesses to prove a charge of treason.
Six Articles repealed.
1548
Easter Sunday - Beverley Minster is suppressed as a collegiate church.
Destruction of the religious colleges of Glasney and Crantock in Cornwall end the formal scholarship that has helped sustain the Cornish language and cultural identity.
John Bale writes Kynge Johan, the earliest English historical drama.
5 December - Cardinal Reginald Pole receives 26 votes at the Papal conclave, only two short of the requisite two-thirds majority to be elected as Pope.