|Covid-19|January 29 – Amadeus IX becomes Duke of Savoy.
January 30 – Charles VIII of Sweden is deposed. Clergyman Kettil Karlsson Vasa becomes Regent of Sweden.
July 13 – Battle of Montlhéry: Troops of King Louis XI of France fight inconclusively against an army of the great nobles organized as the League of the Public Weal.
July 24 – Former King Henry VI of England is captured by Yorkist forces and imprisoned in the Tower of London. His queen consort Margaret of Anjou and Edward of Westminster, Prince of Wales, have fled to France.
August 11 – In Sweden, Regent Kettil Karlsson Vasa, Bishop of Linköping, dies and is succeeded by Archbishop Jöns Bengtsson Oxenstierna as Regent.
October 14 – Wallachian voivode Radu cel Frumos, younger brother of Vlad Țepeș, issues a writ from his residence in Bucharest, the earliest known document to mention the city by name.
Moroccan Revolt in Fez, ousting the Maranid rulers and killing Jews.
Massive flooding in central and southern China motivates the initial construction of hundreds of new bridges.
Main altar of St Martin's Church, Colmar finished by painter Caspar Isenmann
January 1 – Lachlan Cattanach Maclean, 11th Chief, Scottish clan chief (d. 1523)
February 4 – Frans van Brederode, Dutch rebel (d. 1490)
February 6 – Scipione del Ferro, Italian mathematician (d. 1526)
March 16 – Kunigunde of Austria, Archduchess of Austria (d. 1520)
June 10 – Mercurino Gattinara, Italian statesman and jurist (d. 1530)
June 24 – Isabella del Balzo, Queen Consort of Naples (d. 1533)
July 29 – Ichijō Fuyuyoshi, Court noble (d. 1514)
August 17 – Philibert I, Duke of Savoy (d. 1482)
September 11 – Bernardo Accolti, Italian poet (d. 1536)
October 10 – Selim I, sultan of the Ottoman Empire (d. 1520)
October 14 – Konrad Peutinger, German humanist and antiquarian (d. 1547)
December 11 – Ashikaga Yoshihisa, Japanese shogun (d. 1489)
Şehzade Ahmet, oldest son of Sultan Bayezid II (d. 1513)
Hector Boece, Scottish historian (d. 1536)
William Cornysh, English composer (d. 1523)
Johann Tetzel, German Dominican priest (d. 1519)
Diego Velázquez de Cuéllar, Spanish conquistador (d. 1524)
Gil Vicente, Portuguese poet and playwright
Francisco Álvares, Portuguese missionary and explorer (d. 1541)
January 5 – Charles, Duke of Orléans, French poet (b. 1394)
January 14 – Thomas Beckington, English statesman and prelate
January 29 – Louis, Duke of Savoy (b. 1413)
March 30 – Isabella of Clermont, queen consort of Naples (b. c. 1424)
April 30 – Jacob of Juterbogk, theologian (b. c. 1381)
May 12 – Thomas Palaiologos, claimant to Byzantine throne (b. 1409)
August 11 – Kettil Karlsson, regent of Sweden and Bishop of Linköping (plague; b. 1433)
September 25 – Isabella of Bourbon, wife of Charles the Bold (b. 1436)
Abd al-Haqq II, last Marinid Sultan of Morocco (b.1419)
John Hardyng, English chronicler (b. 1378)
Year 1465 (MCDLXV) was a common year starting on Tuesday (link will display the full calendar) of the Julian calendar.