Samiksha Jaiswal (Editor)

1,2,4 Trichlorobenzene

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Appearance
  
Colorless liquid

Boiling point
  
214.4 °C

Density
  
1.46 g/cm³

Formula
  
C6H3Cl3

Molar mass
  
181.45 g/mol

Melting point
  
16.9 °C

1,2,4-Trichlorobenzene File124Trichlorobenzene 2svg Wikimedia Commons

1,2,4-Trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene. It is a derivative of benzene with three chloride substituents. It is a colorless liquid used as a solvent for a variety of compounds and materials.

Contents

1,2,4-Trichlorobenzene 124triclorobenzene Wikipedia

Production and uses

1,2,4-Trichlorobenzene wwwsigmaaldrichcomcontentdamsigmaaldrichstr

Depending on the conditions and additives (e.g., sulfur), it can be the main product from the chlorination of benzene. It is virtually the exclusive product from the chlorination of 1,4-dichlorobenzene. It is also the main product from the dehydrochlorination of hexachlorocyclohexane.

1,2,4-Trichlorobenzene 124trichlorobenzene C6H3Cl3 ChemSynthesis

It is useful as a high-temperature solvent, e.g. for GPC of polyolefines such as PE or PP which are otherwise insoluble.

Aside from its use as a solvent, this compound is a useful precursor to dye and pesticides.

Safety

1,2,4-Trichlorobenzene 124trichlorobenzene C6H3Cl3 PubChem

The LD50 (oral, rats) is 756 mg/kg. Animal studies have shown that 1,2,4-Trichlorobenzene affects the liver and kidney, and is possibly a teratogen. There is no regulated occupational exposure limit for chemical exposure, but the National Institute for Occupational Safety and Health recommends no greater exposure than 5 ppm, over an 8-hour workday.

1,2,4-Trichlorobenzene 124Trichlorobenzene C6H3Cl3 ChemSpider

References

1,2,4-Trichlorobenzene Wikipedia


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