MeSH D017388 | ||
Zygote intrafallopian transfer (ZIFT) is an infertility treatment used when a blockage in the fallopian tubes prevents the normal binding of sperm to the egg. Egg cells are removed from a woman's ovaries, and in vitro fertilised. The resulting zygote is placed into the fallopian tube by the use of laparoscopy. The procedure is a spin-off of the gamete intrafallopian transfer (GIFT) procedure. ZIFT has a success rate of 64.8% in all cases.
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Procedure
The average ZIT cycle takes five weeks to complete. First, the female must take a fertility medication to stimulate egg production in the ovaries. The doctor will monitor the growth of the ovarian follicles, and once they are mature, the woman will receive an injection containing human chorionic gonadotropins (HCG or hCG). The eggs will be harvested approximately 36 hours later, usually by transvaginal ovum retrieval. After fertilization in the laboratory, the resulting early embryos or zygotes are placed into the woman's fallopian tubes using a laparoscope.
Indications
ZIFT has been used in infertility situations where at least one fallopian tube is normal and other treatments have failed; however, the need for two interventions and the fact that IVF results are equal or better (as of 2004), leaves few indications for this procedure. Accordingly, the number of ZIFTs performed has been declining.