Suvarna Garge (Editor)

Zinc finger protein 280b

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Covid-19
Species  Human
Entrez  140883
Human  Mouse
Ensembl  n/a
Aliases  ZNF280B, 5'OY11.1, D87009.C22.3, SUHW2, ZNF279, ZNF632, zinc finger protein 280B
External IDs  MGI: 1927865 HomoloGene: 62794 GeneCards: ZNF280B

Gene music using protein sequence of znf280b zinc finger protein 280b


Zinc finger protein 280B is a protein that in humans is encoded by the ZNF280B gene.

Contents

Function

The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding.

References

Zinc finger protein 280b Wikipedia


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