| 168.14 g/mol|
White to light yellow powder or crystals
Vanillic acid (4-hydroxy-3-methoxybenzoic acid) is a dihydroxybenzoic acid derivative used as a flavoring agent. It is an oxidized form of vanillin. It is also an intermediate in the production of vanillin from ferulic acid.
Vanillic acid Wikipedia
The highest amount of vanillic acid in plants known so far is found in the root of Angelica sinensis, an herb indigenous to China, which is used in traditional Chinese medicine.
Açaí oil, obtained from the fruit of the açaí palm (Euterpe oleracea), is rich in vanillic acid (1,616 ± 94 mg/kg).
It is one of the main natural phenols in argan oil.
It is also found in wine and vinegar.
Vanillic acid is one of the main catechins metabolites found in humans after consumption of green tea infusions.
Oxidation of vanillin to the carboxylic acid occured in ~88% yield.
Vanillic acid is used in the synthesis of:
- the analeptic drug etamivan.
- Vanillic acid is acetylated and converted to its acid chloride; S.B. amidation with bromhexine gives Brovanexine.
- Vanyldisulfamide (need synthesis still).