Aliases TUFT1, entrez:7286 Human Mouse Ensembl ENSG00000143367 | Species Human Entrez 7286 | |
External IDs OMIM: 600087 MGI: 109572 HomoloGene: 7985 GeneCards: TUFT1 | ||
Tuftelin is an acidic phosphorylated glycoprotein found in tooth enamel. In humans, the Tuftelin protein is encoded by the TUFT1 gene.
Contents
Function
This protein is formed for a short time during amelogenesis. The function of tuftelins is under contention, but it is proposed that it acts to start the mineralization process of enamel during tooth development.
Other significant proteins in enamel are amelogenins, enamelins, and ameloblastins.
Research
The human encoding gene for tuftelin (TUFT1) was cloned by Profs. Dany Deutsch and Aharon Palmon from the Hebrew University-Hadassah School of Dental Medicine in Jerusalem.
Interactions
Tuftelin has been shown to interact with TFIP11.
References
Tuftelin Wikipedia(Text) CC BY-SA