Formula C19H15Cl Density 1.14 g/cm³ Appearance white to yellow solid | Molar mass 278.7754 g/mol Boiling point 230 °C | |
Triphenylmethyl chloride or trityl chloride (TrCl) is a white solid with the chemical formula C19H15Cl. It is an alkyl halide, sometimes used to introduce the trityl protecting group.
Contents
Preparation
Triphenylmethyl chloride is commercially available. It may be prepared by the reaction of triphenylmethanol with acetyl chloride, or by the Friedel-Crafts alkylation of benzene with carbon tetrachloride to give the trityl chloride-aluminium chloride adduct, which is then hydrolyzed.
Reactions
Triphenylmethylsodium can be prepared from trityl chloride dissolved in an aprotic solvent and sodium:
(C6H5)3CCl + 2 Na → (C6H5)3CNa + NaClReaction with silver hexafluorophosphate gives triphenylmethyl hexafluorophosphate.
References
Triphenylmethyl chloride Wikipedia(Text) CC BY-SA