Density 1.49 g/cm³ Boiling point 40 °C (104 °F; 313 K) Pubchem 9845 | Formula C4F6O3 Molar mass 210.03 g·mol−1 Melting point −65 °C (−85 °F; 208 K) | |
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EU classification (DSD) Harmful (Xn); Corrosive (C) | ||
Trifluoroacetic anhydride
Trifluoroacetic anhydride (TFAA) is the acid anhydride of trifluoroacetic acid. It is the perfluorinated derivative of acetic anhydride. Like many acid anhydrides, it may be used to introduce the corresponding trifluoroacetyl group. The corresponding acyl chloride, trifluoroacetyl chloride, is a gas, making it inconvenient to work with. Trifluoroacetic anhydride is the recommended desiccant for trifluoroacetic acid.
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Preparation
Trifluoroacetic anhydride may be prepared from trifluoroacetic acid by dehydrating with excess α-halogenated acid chlorides. For example, with dichloroacetyl chloride:
2 CF3COOH + Cl2CHCOCl → (CF3CO)2O + Cl2CHCOOH + HClReferences
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