Formula C9H9NO2S R-phrases R23/24/25 | Molar mass 195.24 g/mol S-phrases S36/37 S45 | |
![]() | ||
Melting point 109 to 113 °C (228 to 235 °F; 382 to 386 K) |
Toluenesulfonylmethyl isocyanide or TOSMIC is an organic compound with the formula CH3C6H4SO2CH2NC. The molecule contains both sulfonyl and isocyanide groups. It is a colourless solid that unlike many isocyanides, is odorless. It is prepared by dehydration of the related formamide derivative. It is used in the Van Leusen reaction which is used to convert aldehydes to nitriles or in the preparation of oxazoles and imidazoles. The versatility of TosMIC in orgnic synthesis has been documented.
References
TosMIC Wikipedia(Text) CC BY-SA