Trade names Vagistat-1 Routes of
administration Topical Synonyms Thioconazole Molar mass 387.711 g/mol | AHFS/Drugs.com Monograph Legal status US: OTC CAS ID 65899-73-2 Trade name Vagistat-1 | |
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ATC code D01AC07 (WHO) G01AF08 (WHO) | ||
Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by a fungus or yeast. It is marketed under the brand names Trosyd and Gyno-Trosyd (Pfizer). Tioconazole ointments serve to treat women's vaginal yeast infections. They are available in one day doses, as opposed to the 7-day treatments more common in use in the past.
Contents
Tioconazole topical (skin) preparations are also available for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus".
Side effects
Side effects (for the women's formulas) may include temporary burning/irritation of the vaginal area, moderate drowsiness, headache similar to a sinus headache, hives, and upper respiratory infection. These side effects may be only temporary, and do not normally interfere with the patient's comfort enough to outweigh the end result.
Synthesis
Antimycotic imidazole derivative.
A displacement reaction between 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol and 2-chloro-3-(chloromethyl)thiophene is performed.
