The Teles Pires (Portuguese: Rio São Manuel) is a 1370 km long river in Brasil. The river flows through the state of Mato Grosso and its lower part marks the border between the states of Mato Grosso and Pará. At its mouth it joins Juruena River and together they form the Tapajós, which is one of the biggest tributaries of the Amazon River. The most important settlement along the river is Alta Floresta.
Several dams are planned on the river in the "Hidrovia Tapajos/Teles Pires" project to create a navigable waterway connecting the interior of Brazil to the Atlantic Ocean. The waterway will consist of five dams on the Teles Pires river (53 megawatts (71,000 hp) Magessi Dam, 430 megawatts (580,000 hp) Sinop Dam, 342 megawatts (459,000 hp) Colíder Dam, 1,820 megawatts (2,440,000 hp) Teles Pires Dam, 746 megawatts (1,000,000 hp) Sao Manoel Dam) and the 5,230 megawatts (7,010,000 hp) Foz do Apiacas Dam on the Apiacas river.
The Colíder Dam and the Teles Pires Dam are currently under construction, while the smaller upstream dams are still in the planning stages.