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Taxifolin 8 monooxygenase

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EC number  1.14.13.19
IntEnz  IntEnz view
ExPASy  NiceZyme view
CAS number  39307-19-2
BRENDA  BRENDA entry
KEGG  KEGG entry

In enzymology, a taxifolin 8-monooxygenase (EC 1.14.13.19) is an enzyme that catalyzes the chemical reaction

taxifolin + NAD(P)H + H+ + O2 2,3-dihydrogossypetin + NAD(P)+ + H2O

The 5 substrates of this enzyme are taxifolin, NADH, NADPH, H+, and O2, whereas its 4 products are 2,3-dihydrogossypetin, NAD+, NADP+, and H2O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is taxifolin,NAD(P)H:oxygen oxidoreductase (8-hydroxylating). This enzyme is also called taxifolin hydroxylase. It has 2 cofactors: FAD, and Flavoprotein.

References

Taxifolin 8-monooxygenase Wikipedia


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