Neha Patil (Editor)

TMEM123

Updated on
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Covid-19
Species  Human
Entrez  114908
Human  Mouse
Ensembl  ENSG00000152558
TMEM123
Aliases  TMEM123, KCT3, PORIMIN, PORMIN, transmembrane protein 123
External IDs  MGI: 1919179 HomoloGene: 14177 GeneCards: TMEM123

Porimin is a protein that in humans is encoded by the TMEM123 gene.

This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.

References

TMEM123 Wikipedia


Similar Topics
The Defender (1988 film)
Beverly Buchanan
Lee Maracle
Topics
 
B
i
Link
H2
L