Species Human Entrez 9014 | Human Mouse Ensembl ENSG00000115750 | |
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Aliases TAF1B, MGC:9349, RAF1B, RAFI63, SL1, TAFI63, TATA-box binding protein associated factor, RNA polymerase I subunit B External IDs MGI: 109577 HomoloGene: 31331 GeneCards: TAF1B | ||
TATA box-binding protein-associated factor RNA polymerase I subunit B is an enzyme that in humans is encoded by the TAF1B gene.
Contents
Function
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs.
Interactions
TAF1B has been shown to interact with RRN3.
References
TAF1B Wikipedia(Text) CC BY-SA