**Scientific pitch notation** (or **SPN**, also known as *American Standard Pitch Notation* (**ASPN**) and *International Pitch Notation* (**IPN**)) is a method of specifying musical pitch by combining a musical note name (with accidental if needed) and a number identifying the pitch's octave.

Although scientific pitch *notation* (SPN) was originally designed as a companion to "scientific pitch" (see below), the two are not synonymous, and should not be confused. Scientific *pitch* is a pitch *standard*—a system which defines the specific frequencies of particular pitches (see below). SPN concerns only how pitch names are *notated*, that is, how they are designated in printed and written text, and does not inherently specify actual frequencies. Thus the use of SPN to distinguish octaves does not depend on the pitch standard used.

The octave number increases by 1 upon an ascension from B to C (and *not* from G♯ to A, as one might expect). Thus "A_{4}" refers to the first A *above* C_{4} (middle C). In describing musical pitches, enharmonic spellings can give rise to anomalies where C♭_{4} is a lower frequency than B♯_{3}; such paradoxes do not arise in a scientific context.

Scientific pitch notation is often used to specify the range of an instrument. It provides an unambiguous means of identifying a note in terms of textual notation rather than frequency, while at the same time avoiding the transposition conventions that are used in writing the music for instruments such as the clarinet and guitar. It is also easily translated into staff notation, as needed.

Other traditional octave naming systems—where for example C_{0} is written as **′′C**, or **C͵͵** or **CCC** in Helmholtz pitch notation, or referred to as subcontra C, and where C_{4} is written as c′ or one-lined C—applies to the written notes that may or may not be transposed. For example, a d′ played on a B♭ trumpet is actually a C_{4} in scientific pitch notation.

Scientific pitch notation avoids possible confusion between various derivatives of Helmholtz notation which use similar symbols to refer to different notes. For example, "c" in Helmholtz notation refers to the C below middle C, whereas "c" in ABC Notation refers to middle C itself. With scientific pitch notation, middle C is *always* **C**_{4}, and **C**_{4} is never any note but middle C. This notation system also avoids the "fussiness" of having to visually distinguish between, say, four and five primes, as well as typographic issues involved in producing acceptable subscripts or substitutes for them. **C**_{7} is much easier to quickly distinguish visually from **C**_{8}, than is, for example, **c′′′′** from **c′′′′′**, and the use of simple integers makes subscripts unnecessary altogether.

Although pitch notation is intended to describe audible sounds, it can also be used to specify the frequency of non-audible phenomena. For example, when the Chandra X-ray Observatory observed the waves of pressure fronts propagating away from a black hole, the one oscillation every 10 million years was described by NASA as corresponding to the B♭ fifty-seven octaves below middle C (or B♭_{−53}).

There are pitch-octave notation conventions that appear similar to scientific pitch notation but are based on an alternative octave convention that differs from scientific pitch notation usually by one octave. For example, some MIDI software uses "C_{5}" to represent middle C (MIDI note 60). This differentiation is unnecessary and can result in confusion.

Using scientific pitch notation consistently, the MIDI NoteOn message assigns MIDI note 0 to C_{−1} (five octaves below C_{4} or Middle C), MIDI note 21 to A_{0} (the bottom key of an 88-key piano), MIDI note 60 to C_{4} (Middle C), MIDI note 69 to A_{4} (A440), MIDI note 108 to C_{8} (the top key of an 88-key piano), and MIDI note 127 to G_{9} (beyond the piano or most instrument ranges).

This creates a linear pitch space in which an octave spans 12 semitones, where each semitone is the distance between adjacent keys of the piano keyboard. Distance in this space corresponds to musical pitch distance in an equal-tempered scale; 2 semitones being a whole step, 1 semitone being a half step. An equal-tempered semitone can also be subdivided further into 100 cents. Each cent is ^{1}⁄_{100} semitone or ^{1}⁄_{1200} octave. This measure of pitch allows the expression of *microtones* not found on standard piano keyboards.

The notation is sometimes used in the context of meantone temperament, and does not always assume equal temperament nor the standard concert A_{4} of 440 Hz; this is particularly the case in connection with earlier music.

The standard proposed to the Acoustical Society of America explicitly states a logarithmic scale for frequency, which excludes meantone temperament, and the base frequency it uses gives A_{4} a frequency of exactly 440 Hz. However, when dealing with earlier music that did not use equal temperament, it is understandably easier to simply refer to notes by their closest modern equivalent, as opposed to specifying the difference using cents every time.

The table below gives notation for pitches based on standard piano key frequencies, in other words, standard concert pitch and twelve-tone equal temperament). When a piano is tuned to just intonation, C_{4} refers to the same key on the keyboard, but a slightly different frequency.

Mathematically, given the number
n
of semitones above middle C, the frequency in hertz is given by
440
⋅
2
(
n
−
9
)
/
12
(see twelfth root of two). Given the MIDI number
m
, the frequency is
440
⋅
2
(
m
−
69
)
/
12
Hz.

Scientific pitch (q.v.) is an absolute pitch *standard*, first proposed in 1713 by French physicist Joseph Sauveur. It was defined so that all Cs are integer powers of 2, with middle C (C_{4}) at 256 hertz. As already noted, it is not dependent upon, nor a part of scientific pitch *notation* described here. To avoid the confusion in names, scientific pitch is sometimes also called "Verdi tuning" or "philosophical pitch".

The current international pitch standard, using A_{4} as exactly 440 Hz, had been informally adopted by the music industry as far back as 1926, and A440 became the official international pitch standard in 1955. SPN is routinely used to designate pitch in this system, and A_{4} may be tuned to other frequencies under different tuning standards as well, and SPN octave designations still apply (ISO 16).

With changes in concert pitch and the widespread adoption of A 440 as a musical standard, new scientific frequency tables were published by the Acoustical Society of America in 1939, and adopted by the International Organization for Standardization in 1955. C_{0}, which was exactly 16 Hz under the scientific pitch standard, is now 16.352 Hz under the current international standard system.

In very recent times scientific pitch (Verdi pitch) has become associated with calls to reestablish a lower musical pitch standard.