The first significant work in astronomy in South Africa was performed by Nicolas Louis de Lacaille between 1751 and 1753, culminating in the measurement of the arc of the southern meridian and a catalog of almost 10 000 southern stars, later published as Coelum Australe Stelliferum.
The Royal Observatory was established at the Cape of Good Hope in 1820 and opened in 1829. Today, with the main observing site having moved from the Cape of Good Hope to a higher site near Sutherland, it is host to the Southern African Large Telescope as well as numerous other South African and international telescopes.
Notable astronomers who have worked in the country include John Herschel who published Results of astronomical observations made during the years 1834, 5, 6, 7, 8, at the Cape of Good Hope in 1847 and David Gill whose work include the Cape Photographic Durchmusterung.
The Karoo Array Telescope (or MeerKAT) is under construction as a pathfinder for the $2 billion Square Kilometer Array (SKA) project, which will be split between sites in South Africa, Australia and New Zealand.
Science and technology in South Africa Wikipedia
Being rich in coal, South Africa has some of the largest coal-fired power stations in the world.
In 1955 Sasol opened the first commercial Coal liquefaction plant.
Commercialization of copper indium gallium sulphur selenide (CIGSSE) thin film solar cell technology was pioneered by Professor Vivian Alberts at the University of Johannesburg.
The South African Solar Challenge is held bi-annually over a distance of 2,500 miles (4,000 km).
As of 2011 the Koeberg Nuclear Power Station is the only commercial nuclear energy station on the African continent.
Kimberley, was the first city in the Southern Hemisphere and in Africa to have electric street lights - first lit on 1 September 1882 .
South African companies hold a considerable number of high value patents related to mining. 10% of the gross domestic product (GDP) of South Africa is generated by mining companies such as De Beers Consolidated Mines , the Anglo American Group and others. They also produce over 50,000 jobs nationally. Mafube Coal Mine near middleburg, Mpumalanga is one of the largest and is operated by Anglo Coal, a division of the Anglo American Group. Since grassroots stages in September 2004, this project's estimated net worth is at ZAR$16 Billion Africa Mining IQ lists along with project history.
BHP Billiton, one of the foremost mining companies in South Africa as well as Sasol Mining, Xstrata and PetroSA are also in large-scale operations.
During the 1960s and 1980s South Africa had been pursuing research into the development of nuclear weapons as well as biological and chemical weapons. South Africa was able to acquire Uranium from native ore deposits, and used aerodynamic nozzle enrichment techniques to produce weapons-grade Uranium. Six bombs were constructed, with one still under construction before the termination of its nuclear weapons programme. It is alleged that South Africa had been collaborating with Israel to develop nuclear weapons and that it possibly detonated one of its weapons over the Indian Ocean in a nuclear weapons test. South Africa dismantled its nuclear weapons programme in 1989, the first nation in the world to do so, and became a signatory of the Nuclear Non-Proliferation Treaty in 1991.
South Africa continues to use its surplus of Uranium as part of its nuclear energy programme, supplying the Koeberg Nuclear Power Station and SAFARI-1 research reactors.
Despite government efforts to encourage entrepreneurship in biotechnology, information technology and other high technology fields, not many notable groundbreaking companies have been founded in South Africa. It is the expressed objective of the government to transition the economy to be more reliant on high technology, based on the realisation that South Africa cannot compete with Far Eastern economies in manufacturing, nor can the republic rely on its mineral wealth in perpetuity.1.5 Mya - Earliest evidence of controlled use of fire by humans at Swartkrans
1882, 1 September - Kimberley becomes the first city in the Southern Hemisphere and in Africa to have electric street lights.
1920 - Hendrik van der Bijl publishes The thermionic vacuum tube and its applications. The standard textbook on the subject of vacuum tubes for more than 20 years.
1937 - The 17-D Yellow Fever vaccine is announced by Max Theiler
1945 - Council for Scientific and Industrial Research was founded
1955 - SASOL produces its first automotive fuel from coal
1959 - Trevor Wadley invented the Tellurometer, the first successful microwave distance measurement device.
1962 - SANAE I, the first South African Antarctic base is built.
1963 - The Dolos was developed in East London
1965, 18 March - SAFARI-1, the first nuclear reactor on the African continent, goes critical
1967, 3 December - The first successful human-to-human heart transplant was performed by Christiaan Barnard at Groote Schuur Hospital
1974 - The first automated pool cleaner, the Kreepy Krauly, was introduced by Ferdinand Chauvier
1975 - Development is started on a helmet mounted sight system and the South African Air Force later become the first country to deploy these during combat.
1978 - SAR Class 6E1 (No. E1525) sets the narrow gauge land speed record for rail vehicles at 245 km/h (152 mph).
1995 - Mark Shuttleworth founded Thawte, an early Internet security company which is now the second largest certificate authority on the internet.
1995 - The Natal Sharks Board starts marketing of the Shark POD, a personal device to deter sharks.
1999, 23 February - SUNSAT, the first South African produced satellite was put in orbit by an American Delta II launch vehicle.
1951, Max Theiler, Nobel Prize in Physiology or Medicine for his work on producing a Yellow fever vaccine
1979, Allan McLeod Cormack, Nobel Prize in Physiology or Medicine for pioneering work in X-ray computed tomography
2002, Sydney Brenner, Nobel Prize in Physiology or Medicine for pioneering work in molecular biology
Minor planet 5038 Overbeek, discovered May 31, 1948, is named after South African astronomer Michiel Daniel Overbeek.
Minor planet 23182 Siyaxuza, discovered July 23, 2000 by the Lincoln Near-Earth Asteroid Research team, is named after South African scientist Siyabulela Xuza.