Samiksha Jaiswal (Editor)

SPIB

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Species
  
Entrez
  
6689

Human
  
Ensembl
  
ENSG00000269404

SPIB

Aliases
  
SPIB, SPI-B, Spi-B transcription factor

External IDs
  
MGI: 892986 HomoloGene: 79220 GeneCards: SPIB

Transcription factor Spi-B is a protein that in humans is encoded by the SPIB gene.

Contents

Function

SPI1 (MIM 165170) and SPIB are members of a subfamily of ETS (see ETS1; MIM 164720) transcription factors. ETS proteins share a conserved ETS domain that mediates specific DNA binding. SPIB and SPI1 bind to a purine-rich sequence, the PU box (5-prime-GAGGAA-3-prime).[supplied by OMIM]

Interactions

SPIB has been shown to interact with MAPK3 and MAPK8.

References

SPIB Wikipedia


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