Species Human Entrez 54345 | Human Mouse Ensembl ENSG00000203883 | |
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Aliases SOX18, HLTS, HLTRS, SRY-box 18 External IDs MGI: 103559 HomoloGene: 7546 GeneCards: SOX18 | ||
Transcription factor SOX-18 is a protein that in humans is encoded by the SOX18 gene.
Contents
Function
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.
Interactions
SOX18 has been shown to interact with MEF2C.
References
SOX18 Wikipedia(Text) CC BY-SA