Species Human Entrez 6423 | Human Mouse Ensembl ENSG00000145423 | |
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Aliases SFRP2, FRP-2, SARP1, SDF-5, secreted frizzled related protein 2 External IDs MGI: 108078 HomoloGene: 56438 GeneCards: SFRP2 | ||
Secreted frizzled-related protein 2 is a protein that in humans is encoded by the SFRP2 gene.
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.
References
SFRP2 Wikipedia(Text) CC BY-SA