Aliases SAP130 Human Mouse Ensembl ENSG00000136715 | Species Human Entrez 79595 | |
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External IDs MGI: 1919782 HomoloGene: 11577 GeneCards: SAP130 | ||
Histone deacetylase complex subunit SAP130 is an enzyme that in humans is encoded by the SAP130 gene.
Contents
Function
SAP130 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003).[supplied by OMIM]
Interactions
SAP130 has been shown to interact with:
Model organisms
Model organisms have been used in the study of SAP130 function. A conditional knockout mouse line called Sap130tm1a(KOMP)Mbp was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping
References
SAP130 Wikipedia(Text) CC BY-SA