Kalpana Kalpana (Editor)

RuvB like 1

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Species
  
Entrez
  
8607

Human
  
Ensembl
  
ENSG00000175792

RuvB-like 1 journalsplosorgplosonearticlefigureimageid

Aliases
  
RUVBL1, ECP54, INO80H, NMP238, PONTIN, Pontin52, RVB1, TIH1, TIP49, TIP49A, ECP-54, NMP 238, RuvB like AAA ATPase 1

External IDs
  
MGI: 1928760 HomoloGene: 37839 GeneCards: RUVBL1

RuvB-like 1 (E. coli), also known as RUVBL1 and TIP49, is a human gene. RUVBL1 can form a hexamer. The hexamer can form a dodecamer with RUVBL2 protein. Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase activity.

Interactions

RuvB-like 1 has been shown to interact with:

  • ACTL6A,
  • Beta-catenin,
  • EP400,
  • Myc, and
  • RUVBL2.
  • References

    RuvB-like 1 Wikipedia


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