Biazon was born on April 14, 1935 in Batac City, Ilocos Norte. His father Rufino Biazon, was a doughmaker then, while his mother Juliana Gaspar, was a clotheswasher. His father died and left him along with his mother and three younger sisters when he was seven years old. At a young age of eight, he and his sisters had already experienced hardship, especially during the Japanese regime. Living in a makeshift shanty in Cavite, they had to peddle food, collected bottles and newspapers, which were later sold in order to earn a living for the family. In spite of their condition, it did not stop him from obtaining his education.
He enrolled as a Grade One student at the age of eleven, in 1946. In order to support his education, and at the same time look for ways to earn money, so he went to school in the morning and worked in the afternoon. He would collect seashells in Manila Bay which were in turn sold at the market. He studied in Jose Rizal Elementary School, Pasay City, for his primary education where he graduated salutatorian. He continued working, washing clothes for other people in order to sustain his high school education at the Jose Abad Santos High School located at the Arellano University, Pasay City in 1955. He also graduated from this school with honors. He stopped doing laundry and instead worked as a laborer in then Highway 54 now known as EDSA, this time to sustain his college education in FEATI where he took mechanical engineering.
He also attended other trainings or schooling which include the TOP Management Program at the Asian Institute of Management; Command and General Staff Course in Quantico, Virginia, U.S.; Crisis Program in California, U.S.; Allied Combat Intelligence Course in Okinawa, Japan; Senior Officer Maintenance Course in Kentucky, U.S.; Amphibious Warfare Course in Quantico, Virginia, U.S. and, Military Instructors in Norfolk, Virginia, United States.
He entered the Philippine Military Academy in 1957, although he applied and passed for the US Navy. He was the class goat of PMA Class 1961 yet this did not prevent him from achieving his goal.
As a soldier, he attained the following posts: Superintendent of PMA in 1986-87, Commandant of the Philippine Marines (PMC) in 1987-89, Commanding General of the NCR Defense Command in 1988-90, Armed Forces of the Philippines (AFP) Vice Chief of Staff in 1990-91 and Armed Forces of the Philippines Chief of Staff in 1991.
He was assigned in Davao in 1983 during the Marcos regime. It was the time when the trust and confidence of the civilians in the military were returned as he took the initiative to do so.
During his tenure both as the Commanding General of the AFP NCR Defense Command and Commandant of the Philippine Marine Corps, he made a mark that truly serves as an inspiration in the soldiers' task of defending the democracy of the nation and further strengthening the Marines. In the height of the 1989 Philippine coup attempt by the Reform the Armed Forces Movement (RAM), led by Col. Gringo Honasan, the Marines and the officers and men of the AFP NCR Defense Command under his humble and dedicated leadership, came out as the defenders of the Republic by quelling the rebels' attack on the General Headquarters of the Armed Forces of the Philippines in Camp Aguinaldo with total bravery and dashing combat skills. The image of the PMC was redeemed after this event, as the public's memory of the PMC's role during the 1986 EDSA Revolution was still fresh. More over, Biazon was hailed as a hero not only by the Aquino government, but also by the general public.
Receiving the full trust and confidence of then President Cory Aquino, his commander in chief, Gen. Biazon was chosen to be the third Armed Forces Chief of Staff of the 5th Republic, after Fidel V. Ramos and Renato de Villa, and the first one to come from the ranks of the PMC on 1991. Prior to that, he served then also as the Vice Chief of Staff of the AFP under De Villa.
He became Senator in the Ninth Congress from 1992 up to 1995. Paul Aquino, the brother of the late Senator Benigno Aquino, Jr. was the one who convinced him to run for office.
He was again elected as Senator in 1998 and continues to serve his term up to 2010.
He was the Chairman of the Senate Committee on National Defense and Security and Committee on Urban Planning, Housing and Resettlement.
Aside from this, he holds the following positions in the Senate: Vice-Chair of the Committees on Agriculture and Food and Foreign Relations, and a Member of 15 other Senate Committees.
He is also the President of the Asian Regional Council Global Parliamentarians on Habitat, the Vice-President for Asia Global Parliamentarians on Habitat, the Co-chairperson of the Philippine Legislators' Committee on Population and Development Foundation, Inc. (PLCPD) and a member of the Commission on Appointments.
Biazon run for re-election and won in 2004 narrowly beating Senator Robert Barbers by margin of 10,685. Barbers filed an electoral protest but died within the year. Biazon continued filling numerous bills and resolution many of them were passed into law, some of them:Republic Act No. 9208, Anti-Trafficking in Persons Act,
Republic Act No. 9161, reforming the renting industry
Republic Act No. 7835, Comprehensive and Integrated Shelter Finance Act,
Republic Act No. 7898, An Act providing for the Modernization of the Armed Forces of the Philippines,
Republic Act No. 7742, changing the mandatory membership to the Pag-Ibig Fund
Republic Act No. 7901, creation of the region of Caraga (Region XIII)
Republic Act No. 7889, establishing the University of the Philippines Mindanao
Republic Act No. 7863, the Home Guaranty Corporation Law
Republic Act No. 7691, Expanding the Jurisdiction of MTC’s, MCTC and METC,
Joint Resolution No. 7, increasing the subsistence allowance of soldiers and policemen,
Republic Act No. 8763, amending the Home Guarantee Corporation Act
Republic Act No. 9040, tax exemption of allowances and benefits for members of the Armed Forces of the Philippines
Republic Act No. 9049, granting monthly gratuity and privileges to awardes of the Medal of Valor
He was also one of the main proponent of the Reproductive Health Bill.
Biazon ran for the open seat of his son, Ruffy in the lone district in 2010 as he was term-limited. Ruffy also term-limited ran instead for the Senate but lost at fourteenth place. He faced former broadcaster Dong Puno. He was elected with 46% of the vote. His term started on June 30, 2010.
He met Ms. Monserrat Narag Bunoan as a classmate in the Philippine Military Academy. Eight months after his graduation in the Philippine Military Academy, he eventually married Monserrat or "Monchie" as she is called.
They have three children, Rita Rosanna, Rino Rudiyardo and Rozzano Rufino (three time Muntinlupa City Congressman; married to Trina Biazon), who were all successful in their own fields.