Species Human Entrez 6241 | Human Mouse Ensembl ENSG00000171848 | |
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Aliases RRM2, R2, RR2, RR2M, ribonucleotide reductase regulatory subunit M2 External IDs MGI: 98181 HomoloGene: 20277 GeneCards: RRM2 | ||
Ribonucleoside-diphosphate reductase subunit M2, also known as ribonucleotide reductase small subunit, is an enzyme that in humans is encoded by the RRM2 gene.
Contents
Function
This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini.
Interactive pathway map
Click on genes, proteins and metabolites below to link to respective articles.
References
RRM2 Wikipedia(Text) CC BY-SA