Species Human Entrez 26994 | Human Mouse Ensembl ENSG00000123091 | |
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Aliases RNF11, SID1669, CGI-123, ring finger protein 11 External IDs MGI: 1352759 HomoloGene: 32195 GeneCards: RNF11 | ||
RING finger protein 11 is a protein that in humans is encoded by the RNF11 gene.
Contents
Function
The protein encoded by this gene contains a RING-H2 finger motif, which is known to be important for protein-protein interactions. The expression of this gene has been shown to be induced by mutant RET proteins (MEN2A/MEN2B). The germline mutations in RET gene are known to be responsible for the development of multiple endocrine neoplasia (MEN).
Interactions
RNF11 has been shown to interact with RIPK1 and STAMBP.
References
RNF11 Wikipedia(Text) CC BY-SA