Kalpana Kalpana (Editor)

Protalix BioTherapeutics

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Type
  
Public

Products
  
Elelyso

Headquarters
  
Karmiel, Israel

Founder
  
Yoseph Shaaltiel

Number of employees
  
266 (2013)

Industry
  
Biotechnology

Website
  
www.protalix.com

Revenue
  
11.51 million USD (2013)

Founded
  
1993

Total assets
  
113.3 million USD (2013)

Protalix BioTherapeutics biotechstockscomwpcontentuploads201701Prota

Traded as
  
NYSE MKT: PLX TASE: PLX

Key people
  
Shlomo Yanai (Interim Chairman) Moshe Manor (CEO)

Stock price
  
PBD (FRA) € 1.06 -0.02 (-1.86%)28 Mar, 8:05 AM GMT+2 - Disclaimer

Protalix biotherapeutics inc plx stock chart technical analysis for 12 28 16


Protalix BioTherapeutics is an Israeli pharmaceutical company whose plant-based enzyme, taliglucerase alfa, has been approved by the U.S. Food and Drug Administration for the treatment of Gaucher disease.

Contents

Protalix biotherapeutics inc plx stock chart technical analysis for 12 14 16


Corporate history

Protalix BioTherapeutics was established in 1993. It was founded by Yoseph Shaaltiel, who received his Ph.D. in Plant Biochemistry from the Weizmann Institute in Israel and served in the Biology Department of the Israel Defense Forces' Biological and Chemical Center. One of the earliest and largest investors in the company was Phillip Frost.

In its early days Protalix operated out of a warehouse in the town of Qiryat Shemona in northern Israel. On July 19, 2005, Protalix Biotherapeutics announced the closing of a $5.3 million private placement of its series C preferred stock. Protalix entered into a partnership agreement with Teva Pharmaceutical Industries in 2006 for the development of two proteins and in 2009 signed a collaboration agreement with Pfizer for the development and commercialization of its taliglucerase alfa treatment. Also in 2009, Protalix reported that Frost & Sullivan presented the company with its 2009 European Orphan Diseases Market Product Innovation of the Year Award. In 2011 Protalix announced that the U.S. Food and Drug Administration had approved the company's manufacturing facility in Karmiel.

Protalix initially became a public company through a reverse merger process with Orthodontix, a company which was at the time traded "over the counter" on the NASDAQ. This merger was completed on December 31, 2006, and is notable as one of the largest reverse mergers executed, valuing the joint entity at almost $1 billion. It subsequently applied for a listing on the AMEX, and sold 10 million shares in a public offering.

Products

Protalix has been using cultured plant cells to manufacture biopharmaceuticals. As of 2012, Protalix has been developing two such products:

  • Taliglucerase alfa – a recombinant glucocerebrosidase enzyme produced from transgenic carrot cell cultures. Known also as Elelyso, taliglucerase won approval from the U.S. Food and Drug Administration in May 2012 as an orphan drug for the treatment of Type 1 Gaucher's disease.
  • PRX-105 – a recombinant human Acetylcholinesterase, produced from genetically modified cell line of tobacco cells (Nicotiana tabacum), which can be used as a counter-measure against nerve agents attack. PRX-105 completed exploratory Phase I clinical trails.
  • References

    Protalix BioTherapeutics Wikipedia