Plasminogen activator Pla

Plasminogen activator Pla (EC 3.4.23.48) is an enzyme. This enzyme catalyses the following chemical reaction

Converts human Glu-plasminogen to plasmin by cleaving the Arg⁵⁶⁰-Val peptide bond that is also hydrolysed by the mammalian u-plasminogen activator and t-plasminogen activator. Also cleaves arginyl bonds in other proteins

This enzyme is isolated from the bacterium Yersinia pestis that causes plague.