Born in Montargis, Loiret, she initially studied plastic arts, then studied at the Conservatoire de Paris after earning a bachelor's degree in musicology, and won the Conservatory's first prize in 1995.
She made her debut at the Vienna State Opera as Olympia in Offenbach's Les Contes d'Hoffman, a role which she has performed several times in France, including an extravagant production by Jérôme Savary at the Palais Omnisports de Paris-Bercy in 2004.
In 2006, she was one of the soloists in the Mozart 250th birthday celebration in Salzburg, which was telecast on Great Performances by PBS.
In January 2008 Petibon sang in Francis Poulenc's Dialogues des Carmélites at the Theater an der Wien replacing another singer who fell ill. In July of that year Petibon sang in the zarzuela Luisa Fernanda by Federico Moreno Torroba at the Theater an der Wien in Vienna (alongside Plácido Domingo). She also signed an exclusive recording contract with Deutsche Grammophon in 2008. In 2012 Petibon sang as Donna Anna in Don Giovanni and as Susanna in Le nozze di Figaro.
Petibon is married to French composer Eric Tanguy. They have one child.
Solo discography
Airs baroques Français, Patrick Cohen-Akenine, Les Folies Françoises (2002) (Rameau/Lully/Charpentier/Grandaval)
Les Fantasies de Patricia Petibon (2004) [compilation]
French Touch, Yves Abel (2004)
Purcell et l'Italie, Jean-François Novelli, Ensemble Amarillis (2004)