Harman Patil (Editor)

PRKD2

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Species
  
Entrez
  
25865

Human
  
Ensembl
  
ENSG00000105287

PRKD2

Aliases
  
PRKD2, PKD2, nPKC-D2, HSPC187, protein kinase D2

External IDs
  
MGI: 2141917 HomoloGene: 9516 GeneCards: PRKD2

Serine/threonine-protein kinase D2 or PKD2 is an enzyme that in humans is encoded by the PRKD2 gene.

Function

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases, a subfamily of protein kinase c. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.

References

PRKD2 Wikipedia


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