Kalpana Kalpana (Editor)

PPP2R5A

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Species
  
Human

Entrez
  
5525

Human
  
Mouse

Ensembl
  
ENSG00000066027

PPP2R5A

Aliases
  
PPP2R5A, B56A, PR61A, protein phosphatase 2 regulatory subunit B'alpha

External IDs
  
MGI: 2388479 HomoloGene: 55961 GeneCards: PPP2R5A

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform is an enzyme that in humans is encoded by the PPP2R5A gene.

Contents

Function

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily.

Interactions

PPP2R5A has been shown to interact with:

  • AXIN1,
  • CTLA-4,
  • PPP2CA,
  • PPP2R1A, and
  • PPP2R1B.
  • References

    PPP2R5A Wikipedia