Species Human Entrez 5441 | Human Mouse Ensembl ENSG00000177700 | |
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Aliases POLR2L, RBP10, RPABC5, RPB10, RPB10beta, RPB7.6, hRPB7.6, polymerase (RNA) II subunit L External IDs MGI: 1913741 HomoloGene: 129854 GeneCards: POLR2L | ||
DNA-directed RNA polymerases I, II, and III subunit RPABC5 is a protein that in humans is encoded by the POLR2L gene.
Contents
Function
This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases.
Interactions
POLR2L has been shown to interact with POLR2C, POLR2A, POLR2B and POLR2E.
References
POLR2L Wikipedia(Text) CC BY-SA