Neha Patil (Editor)

PIGH

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Species
  
Human

Entrez
  
5283

Human
  
Mouse

Ensembl
  
ENSG00000100564

PIGH

Aliases
  
PIGH, GPI-H, phosphatidylinositol glycan anchor biosynthesis class H

External IDs
  
MGI: 99463 HomoloGene: 3361 GeneCards: PIGH

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Phosphatidylinositol N-acetylglucosaminyltransferase subunit H is an enzyme that in humans is encoded by the PIGH gene. The PIGH gene is located on the reverse strand of chromosome 14 in humans, and is neighbored by TMEM229B.

Contents

This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. The protein encoded by this gene is a subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum.

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Interactions

PIGH has been shown to interact with PIGQ.

References

PIGH Wikipedia