Rahul Sharma (Editor)


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Species  Human
Entrez  9091
Human  Mouse
Ensembl  ENSG00000007541

Aliases  PIGQ, GPI1, c407A10.1, phosphatidylinositol glycan anchor biosynthesis class Q
External IDs  MGI: 1333114 HomoloGene: 31228 GeneCards: PIGQ

Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q is an enzyme that in humans is encoded by the PIGQ gene.

This gene is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI).


PIGQ has been shown to interact with PIGH, PIGA and PIGC.


PIGQ Wikipedia