Species Human Entrez 286530 | Human Mouse Ensembl ENSG00000182162 | |
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Aliases P2RY8, P2Y8, purinergic receptor P2Y8 External IDs HomoloGene: 65345 GeneCards: P2RY8 | ||
P2Y purinoceptor 8 is a protein that in humans is encoded by the P2RY8 gene.
Contents
Function
The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y.
Clinical relevance
Recurrent mutations in this gene have been associated to cases of diffuse large B-cell lymphoma.
References
P2RY8 Wikipedia(Text) CC BY-SA