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An oxaprostaglandin is a type of prostaglandin with one carbon atom replaced by an oxygen atom. These are found in nature and have also been produced synthetically.
Contents
Medical uses
A 13-oxaprostaglandin analogue has been shown to treat glaucoma and ocular hypertension.
The 11-oxa prostaglandin analogue AL-12182 1 has potent topical ocular hypotensive activity.
7-Oxa-13-prostynoic acid promotes erythrocyte lysis and dissolution of erythrocyte membranes.
Synthesis
11-Oxaprostaglandin f2α and 11-oxaprostaglandin f2β have been synthesized from D-glucose
References
Oxaprostaglandin Wikipedia(Text) CC BY-SA