MedlinePlus a682128 CAS Number 61-57-4 UNII N116U8Y5QQ Molar mass 214.2 g/mol ChemSpider ID 5868 | ATC code P02BX02 (WHO) PubChem CID 6093 KEGG D05170 Pubchem 6093 | |
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Medical vocabulary what does niridazole mean
Niridazole is a schistosomicide. It is used to treat schistosomiasis, the helmintic disease caused by certain flatworms (trematodes) from the genus Schistosoma (formerly Bilharzia). It is also known by its trade name Ambilhar. It is usually given as tablets.
Contents
Niridazole has central nervous system toxicity and can cause dangerous side effects, such as hallucinations. Also, it may cause allergic reactions in sensitive people. However, it is one of the most effective schistosomicide drugs.
It has recently also been investigated for use in the treatment of periodontitis.
What does niridazole mean
Mechanism of action
Niridazole is rapidly concentrated in the parasite and inhibits oogenesis and spermatogenesis. The compound also inhibits the phosphofructokinase enzyme, leading to glycogen depletion and hepatic shift.