Supriya Ghosh (Editor)

Neurotensin receptor 1

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Species
  
Human

Entrez
  
4923

Human
  
Mouse

Ensembl
  
ENSG00000101188

Neurotensin receptor 1

Aliases
  
NTSR1, NTR, Neurotensin receptor 1, neurotensin receptor 1 (high affinity)

External IDs
  
MGI: 97386 HomoloGene: 68261 GeneCards: NTSR1

Neurotensin receptor type 1 is a protein that in humans is encoded by the NTSR1 gene. For a crystal structure of NTS1, see pdb code 4GRV.

Contents

Function

Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of testing as many as neurotensin, such as low blood pressure, high blood sugar, low body temperature, antinociception, and regulation of intestinal motility and secretion.

Ligands

  • ML314 – β-arrestin biased agonist
  • References

    Neurotensin receptor 1 Wikipedia