Aliases NOX5 Human Mouse Ensembl ENSG00000255346 | Species Human Entrez 79400 | |
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External IDs HomoloGene: 41568 GeneCards: NOX5 | ||
NADPH oxidase, EF-hand calcium binding domain 5, also known as NOX5, is a protein which in humans is encoded by the NOX5 gene.
Function
NOX5 is a novel NADPH oxidase that generates superoxide.
Nox5 interacts with c-abl, superoxide production leads to phosphorylation of c-abl, while inhibition of c-abl kinase activity inhibits Nox5 superoxide production.
References
NOX5 Wikipedia(Text) CC BY-SA