Entrez 10397 | Ensembl ENSG00000104419 | |
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Aliases NDRG1, CAP43, CMT4D, DRG-1, DRG1, GC4, HMSNL, NDR1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5, N-myc downstream regulated 1 External IDs MGI: 1341799 HomoloGene: 55953 GeneCards: NDRG1 |
Protein NDRG1 is a protein that in humans is encoded by the NDRG1 gene.
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. Mutations in this gene have been reported to be causative the autosomal-recessive version of Charcot-Marie-Tooth disease known as CMT4D. It has been reported that NDRG1 localizes to the endosomes and is a Rab4a effector involved in vesicular recycling.
References
NDRG1 Wikipedia(Text) CC BY-SA