Species Human Entrez 10403 | Human Mouse Ensembl ENSG00000080986 | |
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Aliases NDC80, HEC, HEC1, HsHec1, KNTC2, TID3, hskinetochore complex component External IDs MGI: 1914302 HomoloGene: 38141 GeneCards: NDC80 | ||
Kinetochore protein NDC80 homolog is a protein that in humans is encoded by the NDC80 gene.
Contents
Function
HEC is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.[supplied by OMIM]
Interactions
NDC80 has been shown to interact with MIS12, NEK2 and PSMC2.
References
NDC80 Wikipedia(Text) CC BY-SA