EC number 3.5.1.27 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 37289-08-0 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a N-formylmethionylaminoacyl-tRNA deformylase (EC 3.5.1.27) is an enzyme that catalyzes the chemical reaction
N-formyl-L-methionylaminoacyl-tRNA + H2OThus, the two substrates of this enzyme are N-formyl-L-methionylaminoacyl-tRNA and H2O, whereas its two products are formate and L-methionylaminoacyl-tRNA.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-formyl-L-methionylaminoacyl-tRNA amidohydrolase. This enzyme participates in glyoxylate and dicarboxylate metabolism.
Structural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1BSJ, 1BSK, and 1LMH.
References
N-formylmethionylaminoacyl-tRNA deformylase Wikipedia(Text) CC BY-SA