Nα benzyloxycarbonylleucine hydrolase

In enzymology, N^α-benzyloxycarbonylleucine hydrolase (EC 3.5.1.64) is an enzyme that catalyzes the chemical reaction

N^α-benzyloxycarbonyl-L-leucine + H₂O ⇌ benzyl alcohol + CO₂ + L-leucine

Thus, the two substrates of this enzyme are N^α-benzyloxycarbonyl-L-leucine and H₂O, whereas its three products are benzyl alcohol, CO₂, and L-leucine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is Nalpha-benzyloxycarbonyl-L-leucine urethanehydrolase. Other names in common use include benzyloxycarbonylleucine hydrolase, Nalpha-benzyloxycarbonyl amino acid urethane hydrolase IV, and alpha-N-benzyloxycarbonyl-L-leucine urethanehydrolase.