Trisha Shetty (Editor)

Myosin heavy chain kinase

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EC number
  
2.7.11.7

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
64763-54-8

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a myosin-heavy-chain kinase (EC 2.7.11.7) is an enzyme that catalyzes the chemical reaction

ATP + [myosin heavy-chain] ⇌ ADP + [myosin heavy-chain] phosphate

Thus, the two substrates of this enzyme are ATP and myosin heavy-chain, whereas its two products are ADP and myosin heavy-chain phosphate.

This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases). The systematic name of this enzyme class is ATP:[myosin heavy-chain] O-phosphotransferase. Other names in common use include

  • ATP:myosin-heavy-chain O-phosphotransferase
  • calmodulin-dependent myosin heavy chain kinase
  • MHCK
  • MIHC kinase
  • myosin heavy chain kinase
  • myosin I heavy-chain kinase
  • myosin II heavy-chain kinase
  • [myosin-heavy-chain] kinase
  • myosin heavy chain kinase A
  • STK6.

    • References

    Myosin-heavy-chain kinase Wikipedia
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